John Hemming's Web Log

Now this might seem an odd suggestion. However, if you are starting Rapamycin I think you should first photograph your nails. That is because Rapamycin affects the growth of many people's fingernails and you may wish to titrate your usage of Rapamycin by how you see the effects on your nails. Rapamycin is known as an mTOR inhibitor. mTOR is a kinase in each cell that passes signals around relating to cell growth. If mTOR is activated then there is plenty of nutrients and so the cell can get on with building things. If mTOR is inactive it means nutrients are scarce and the cell needs to start recycling things to make them more efficient. Hence inhibiting mTOR (through the use of Rapamycin or fasting) can get the cell to start the process of autophagy The particular aspect of autophagy that is very useful is mitophagy where the cell starts recycling mitochondria. The less efficient mitochondria have a lower MMP (Mitochondrial Membrane Potential) {normally} and the cell auto

Space Medicine Expert Dr Rawan Al Shammari has joined the “Biohacking to improve everyone’s health” XPrize healthspan team headed up by John Hemming who was previously a Member of Parliament, in the UK. Oxford Visiting Professor Dr Richard Siow has also joined the team as the academic advisor. XPrize healthspan is a USD $ 101 Million contest organised by the XPrize foundation as a global contest to see which teams can improve human health by the equivalent of 10-20 years in the three areas of cognition, frailty and immune system. John Hemming is an erstwhile Liberal Democrat Member of Parliament who has successfully run a number of businesses and who has created the “Biohacking to improve everyone’s health” team as part of the XPrize. Dr Rawan Al Shammari is a medical doctor who specialises in Space Medicine. She has been appointed as the medical advisor to the team. Dr Siow has also joined the team as the academic advisor. The team is working to develop a protocol which improve