My eldest daughter pointed out that Dangermouse was dated by the evil supercomputer saying "kneel before my 500 Megabytes". When I was a lad ... we had the SDK 85 which was programmed in machine code and had a memory counted in K.
Trudiagnostic change PACE leaderboard algorithm - was in position 40, now position 44 - does it matter?
Trudiagnostic have changed the way they handle the Rejuvenation Olympics Leaderboard algorithm. The result of this initially was that I was globally no 40 and have now dropped to 44. Trudiagnostic are a US company that get samples of blood and they look at the DNA to see which parts of the DNA have methyl groups (CH3) attached to them. These modifications to DNA are called methylation markers. DunedinPACE is an algorithm which uses DNA methylation markers in white blood cells to work out how quickly or slowly someone is aging. I had three results on this. The odd thing about the results was that whilst my epigenetic age calculated from the same methylation markers was going down, the speed at which I was aging was going up. I find this somewhat counterintuitive. It is, however, I think relevant that in a global contest my approach on biochemistry which is quite different to many other people's does seem to keep up with others working in the same area. To that extent it...
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Multi-user banking systems on PDP-11s with 512k RAM...:)
Then along came Oracle...:)
My first Spectrum had a whopping 16k of memory. My first hard drive was 100Mb, I well remember selling customers PCs and persuading them to upgrade to 16Mb to get better performance out of Windows 3.1. I've still got an elderly iP133 MHz PC sitting on my home network with a decent 1Gb HDD.
I've just bought a new desktop with 2Gb of memory and 300Gb of hard drive to play with.
That sort of pace of change makes me feel very old.