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Election Results 21st January 2010

Erewash BC, West Hallam and Dale Abbey
Con 692 (51.4; -22.6)
LD Gary Hamson 506 (37.6; +37.6)
Lab 149 (11.1; -15.0)
Majority 186
Turnout 33.81%
Con hold
Percentage change is since May 2007.

Wakefield MBC, Airedale and Ferry Fryston
Lab 1330 (49.9; +3.2)
LD Paul Kirby 603 (22.6; +8.3)
BNP 353 (13.3; -7.7)
Con 275 (10.3; -7.7)
Ind 102 (3.8; +3.8)
Majority 727
Turnout 23.39%
Lab hold
Percentage change is since May 2008.

Calne TC, Lickhill
LD Michelle Pearce 331 (80.7)
UKIP 79 (19.3)
Majority 252
Turnout 13.9%
LD gain from Con

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Its the long genes that stop working

People who read my blog will be aware that I have for some time argued that most (if not all) diseases of aging are caused by cells not being able to produce enough of the right proteins. What happens is that certain genes stop functioning because of a metabolic imbalance. I was, however, mystified as to why it was always particular genes that stopped working. Recently, however, there have been three papers produced: Aging is associated with a systemic length-associated transcriptome imbalance Age- or lifestyle-induced accumulation of genotoxicity is associated with a generalized shutdown of long gene transcription and Gene Size Matters: An Analysis of Gene Length in the Human Genome From these it is obvious to see that the genes that stop working are the longer ones. To me it is therefore obvious that if there is a shortage of nuclear Acetyl-CoA then it would mean that the probability of longer Genes being transcribed would be reduced to a greater extent than shorter ones.
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