People who read my blog will be aware that I have for some time argued that most (if not all) diseases of aging are caused by cells not being able to produce enough of the right proteins. What happens is that certain genes stop functioning because of a metabolic imbalance. I was, however, mystified as to why it was always particular genes that stopped working. Recently, however, there have been three papers produced: Aging is associated with a systemic length-associated transcriptome imbalance Age- or lifestyle-induced accumulation of genotoxicity is associated with a generalized shutdown of long gene transcription and Gene Size Matters: An Analysis of Gene Length in the Human Genome From these it is obvious to see that the genes that stop working are the longer ones. To me it is therefore obvious that if there is a shortage of nuclear Acetyl-CoA then it would mean that the probability of longer Genes being transcribed would be reduced to a greater extent than shorter ones.
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Attachment disorder- treatment/ therapy?
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In my placement in children's services, almost every young person I see seems to have a diagnosis of attachment disorder, but it seems few get any sort of help for this, other than possibly a few appointments with CAMHS. Many seem to be placed in residential homes, due to it being recognised they cannot cope with family life following frequent foster placement breakdowns. So it follows that, many, or most, of these children are growing into adults with attachment disorders.
What I'm wondering therefore, as I can't find any information or research about this, is if there are any forms of therapy or treatment that are recognised to be successful with these children/ adults?
I've seen research papers that suggest that attachment problems in childhood are often predisposing factors to the development of borderline personality disorder or other mental health problems- but although attachment disorder seems to be a common 'label' for children, I have never really heard it applied to adults before.
Can anyone help, or point me to any useful articles/ books/ other resources that might provide me some answers?