Many people remember the saga in the past about Green Waste. I took a court case out against the City Council and the City Cleared up the waste, but the court decided to award costs against me. I took this through an appeal in the Admin Court and a second appeal in the Court of Appeal (both of which I lost). I then took it to the Aarhus Convention Compliance Committee where this week I won.
The details are here:
https://unece.org/env/pp/cc/accc.c.2016.142_united-kingdom
It is quite significant as it requires the UK to change its procedures so that people can safely challenge public authorities on environmental issues without worrying about being hit by a hefty costs bill.
The fact is that there were two other people hit by this in the UK and it had shut down one local environmental charity because of the impact.
People who read my blog will be aware that I have for some time argued that most (if not all) diseases of aging are caused by cells not being able to produce enough of the right proteins. What happens is that certain genes stop functioning because of a metabolic imbalance. I was, however, mystified as to why it was always particular genes that stopped working. Recently, however, there have been three papers produced: Aging is associated with a systemic length-associated transcriptome imbalance Age- or lifestyle-induced accumulation of genotoxicity is associated with a generalized shutdown of long gene transcription and Gene Size Matters: An Analysis of Gene Length in the Human Genome From these it is obvious to see that the genes that stop working are the longer ones. To me it is therefore obvious that if there is a shortage of nuclear Acetyl-CoA then it would mean that the probability of longer Genes being transcribed would be reduced to a greater extent than shorter ones.
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