For those that follow this issue. Stuart Syvret who as health minister in Jersey blew the whistle on maltreatment of children has been released from prison again. He was imprisoned for what he said. Yes I know it was contempt of court, but at the end of the day the offence was one of speech. Specifically speech criticising the failure of the authorities in Jersey to prosecute certain individuals.
There is a blog posting about this with a short interview with him here
People who read my blog will be aware that I have for some time argued that most (if not all) diseases of aging are caused by cells not being able to produce enough of the right proteins. What happens is that certain genes stop functioning because of a metabolic imbalance. I was, however, mystified as to why it was always particular genes that stopped working. Recently, however, there have been three papers produced: Aging is associated with a systemic length-associated transcriptome imbalance Age- or lifestyle-induced accumulation of genotoxicity is associated with a generalized shutdown of long gene transcription and Gene Size Matters: An Analysis of Gene Length in the Human Genome From these it is obvious to see that the genes that stop working are the longer ones. To me it is therefore obvious that if there is a shortage of nuclear Acetyl-CoA then it would mean that the probability of longer Genes being transcribed would be reduced to a greater extent than shorter ones.
Comments
its not a fair system more so in Jersey, I do applaud Stuart wholeheartedly and do hope that one day he achieves what he is pursuing despite the pit falls and set backs he faces
A more in-depth, and exclusive, interview with Stuart, filmed on the day of his release can be viewed HERE