People who read my blog will be aware that I have for some time argued that most (if not all) diseases of aging are caused by cells not being able to produce enough of the right proteins. What happens is that certain genes stop functioning because of a metabolic imbalance. I was, however, mystified as to why it was always particular genes that stopped working. Recently, however, there have been three papers produced: Aging is associated with a systemic length-associated transcriptome imbalance Age- or lifestyle-induced accumulation of genotoxicity is associated with a generalized shutdown of long gene transcription and Gene Size Matters: An Analysis of Gene Length in the Human Genome From these it is obvious to see that the genes that stop working are the longer ones. To me it is therefore obvious that if there is a shortage of nuclear Acetyl-CoA then it would mean that the probability of longer Genes being transcribed would be reduced to a greater extent than shorter ones.
Comments
Its better to Jail someone who may be outspoken or are deemed as a threat to the Authorities, I know being in the same position myself last year.
The questions need to be asked and urgent action should be taken against the Authorities and the JUDGES who jail innocent people for committing no crime but chose to speak out about their treatment at the hands of the state.
Best of luck with it, its high time is was properly debated and brought to the public's attention.